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Phoenix Pharmaceuticals pacap elisa kit
Pacap Elisa Kit, supplied by Phoenix Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pacap+elisa+kit/pacap+elisa+kit/pm40409714-75-8-11
Average 90 stars, based on 1 article reviews
pacap elisa kit - by Bioz Stars, 2026-09
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Enzyme-linked Immunosorbent Assay:

Article Title: PACAP inhibits sepsis-associated acute lung injury by inhibiting the Sp1/AQP1 pathway.
Article Snippet: Sepsis-induced acute lung injury (ALI) represents a severe pathological state marked by uncontrolled inflammation, redox imbalance, and alveolar-capillary barrier breakdown.. Here, we evaluated the therapeutic potential of pituitary adenylate cyclase-activating polypeptide (PACAP) in a murine sepsis-ALI model. PACAP treatment notably ameliorated histological damage, reduced oxidative stress biomarkers, and mitigated inflammatory processes, including neutrophil accumulation and pro-inflammatory cytokine release.. Molecular analysis revealed PACAP-mediated downregulation of Aquaporin-1 (AQP1) and specificity protein 1 (Sp1), key regulators of alveolar fluid homeostasis and inflammatory signaling.



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Enhanced PACAP and <t>VIP</t> levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse <t>ELISA</t> Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.
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Enhanced PACAP and <t>VIP</t> levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse <t>ELISA</t> Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.
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Enhanced PACAP and <t>VIP</t> levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse <t>ELISA</t> Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.
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Enhanced PACAP and <t>VIP</t> levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse <t>ELISA</t> Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.
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Enhanced PACAP and <t>VIP</t> levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse <t>ELISA</t> Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.
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Enhanced PACAP and VIP levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse ELISA Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.

Journal: International Journal of Molecular Sciences

Article Title: Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling

doi: 10.3390/ijms25179453

Figure Lengend Snippet: Enhanced PACAP and VIP levels in the cerebrum and cerebellum of GFAP-IL6 mice are partly rescued in bi-genic GFAP-IL6/sgp130Fc mice. PACAP and VIP protein concentrations in lysates from cerebra and cerebella of age-matched six-months-old wild-type (WT), monogenic GFAP-IL6 and bi-genic GFAP-IL6/sgp130Fc mice were determined using commercially available PACAP and VIP mouse ELISA Kits (for details refer to ). Comparisons among WTs, monogenic and bi-genic mice groups (n = 3 per group) were conducted to assess the levels of PACAP or VIP in the cerebrum ( A , B ) and cerebellum ( C , D ). * p < 0.05 or ** p < 0.01 vs. WT. # p < 0.05 or ## p < 0.01 vs. GFAP-IL6 mice. n.s. = not significant. Tukey post-hoc test after analysis of variance.

Article Snippet: PACAP and VIP concentrations in the cerebrum and cerebellum of aged-matched six-month-old WT GFAP-IL6 and GFAP-IL6/sgp130Fc mice were determined using the commercially available PACAP and VIP mouse ELISA Kits (MyBioSource, San Diego, CA, USA, Cat no. MBS2503456 and MBS703048, respectively).

Techniques: Enzyme-linked Immunosorbent Assay