pacap elisa kit (Phoenix Pharmaceuticals)
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Pacap Elisa Kit, supplied by Phoenix Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pacap+elisa+kit/pacap+elisa+kit/pm40409714-75-8-11
Average 90 stars, based on 1 article reviews
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Enzyme-linked Immunosorbent Assay:Article Title: PACAP inhibits sepsis-associated acute lung injury by inhibiting the Sp1/AQP1 pathway. Article Snippet: Sepsis-induced acute lung injury (ALI) represents a severe pathological state marked by uncontrolled inflammation, redox imbalance, and alveolar-capillary barrier breakdown.. Here, we evaluated the therapeutic potential of pituitary adenylate cyclase-activating polypeptide (PACAP) in a murine sepsis-ALI model. PACAP treatment notably ameliorated histological damage, reduced oxidative stress biomarkers, and mitigated inflammatory processes, including neutrophil accumulation and pro-inflammatory cytokine release.. Molecular analysis revealed PACAP-mediated downregulation of Aquaporin-1 (AQP1) and specificity protein 1 (Sp1), key regulators of alveolar fluid homeostasis and inflammatory signaling. |
